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ANT2-Mediated ATP Import into Mitochondria Protects against Hypoxia Lethal Injury

Following a prolonged exposure to hypoxia–reoxygenation, a partial disruption of the ER-mitochondria tethering by mitofusin 2 (MFN2) knock-down decreases the Ca(2+) transfer between the two organelles limits mitochondrial Ca(2+) overload and prevents the Ca(2+)-dependent opening of the mitochondrial...

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Detalles Bibliográficos
Autores principales: Gouriou, Yves, Alam, Muhammad Rizwan, Harhous, Zeina, Crola Da Silva, Claire, Baetz, Delphine Baetz, Badawi, Sally, Lefai, Etienne, Rieusset, Jennifer, Durand, Annie, Harisseh, Rania, Gharib, Abdallah, Ovize, Michel, Bidaux, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760820/
https://www.ncbi.nlm.nih.gov/pubmed/33255741
http://dx.doi.org/10.3390/cells9122542