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Stereoselective Synthesis of the I–L Fragment of the Pacific Ciguatoxins

The I–L ring system found in all the Pacific ciguatoxins has been prepared from a tricyclic precursor in a highly stereoselective manner. Subtle differences in the reactivity of the enones present in the seven- and eight-membered rings of the tricyclic ether starting material have been exploited to...

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Detalles Bibliográficos
Autores principales: Clark, J. Stephen, Popadynec, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760828/
https://www.ncbi.nlm.nih.gov/pubmed/33255410
http://dx.doi.org/10.3390/toxins12120740