Cargando…

Uremic Apelin and Leucocytic Angiotensin-Converting Enzyme 2 in CKD Patients

Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its vaso...

Descripción completa

Detalles Bibliográficos
Autores principales: Trojanowicz, Bogusz, Ulrich, Christof, Girndt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760850/
https://www.ncbi.nlm.nih.gov/pubmed/33255902
http://dx.doi.org/10.3390/toxins12120742