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Uremic Apelin and Leucocytic Angiotensin-Converting Enzyme 2 in CKD Patients

Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its vaso...

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Detalles Bibliográficos
Autores principales:	Trojanowicz, Bogusz, Ulrich, Christof, Girndt, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760850/ https://www.ncbi.nlm.nih.gov/pubmed/33255902 http://dx.doi.org/10.3390/toxins12120742

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