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ADP-Mediated Upregulation of Expression of CD62P on Human Platelets Is Critically Dependent on Co-Activation of P2Y1 and P2Y12 Receptors

This study probed the differential utilization of P2Y1 and P2Y12 receptors in mobilizing CD62P (P-selectin) from intracellular granules following activation of human platelets with adenosine 5′-diphosphate (ADP, 100 µmol·L(−1)) Platelet-rich plasma (PRP) was prepared from the blood of adult humans....

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Detalles Bibliográficos
Autores principales: Anderson, Ronald, Theron, Annette J., Steel, Helen C., Nel, Jan G., Tintinger, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760858/
https://www.ncbi.nlm.nih.gov/pubmed/33255391
http://dx.doi.org/10.3390/ph13120420