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Low Oral Bioavailability and Partial Gut Microbiotic and Phase II Metabolism of Brussels/Witloof Chicory Sesquiterpene Lactones in Healthy Humans

Free and glycosylated sesquiterpene lactones (SLs), which are abundant in leafy vegetables including Brussels/witloof chicory, possess health-promoting effects in vivo. However, the pharmacokinetics of dietary source of SLs remain largely unknown. In this open-label and single-dose trial, sixteen he...

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Detalles Bibliográficos
Autores principales: Weng, Hui, He, Luanying, Zheng, Jiakun, Li, Qing, Liu, Xiuping, Wang, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760865/
https://www.ncbi.nlm.nih.gov/pubmed/33260567
http://dx.doi.org/10.3390/nu12123675