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Centromeric KIR AA Individuals Harbor Particular KIR Alleles Conferring Beneficial NK Cell Features with Implications in Haplo-Identical Hematopoietic Stem Cell Transplantation

SIMPLE SUMMARY: We have recently shown a broad disparity of Natural Killer (NK) cell responses against leukemia, highlighting good and bad responders resting on the Killer cell Immunoglobulin-like Receptors (KIR) and HLA genetics. In this study, we deeply investigated KIR2DL NK cell repertoire in co...

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Detalles Bibliográficos
Autores principales: Dubreuil, Léa, Maniangou, Bercelin, Chevallier, Patrice, Quéméner, Agnès, Legrand, Nolwenn, Béné, Marie C., Willem, Catherine, David, Gaëlle, Alizadeh, Mehdi, Makanga, Dhon Roméo, Cesbron, Anne, Gendzekhadze, Ketevan, Gagne, Katia, Retière, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760878/
https://www.ncbi.nlm.nih.gov/pubmed/33271841
http://dx.doi.org/10.3390/cancers12123595