Bone Morphogenetic Protein 2 (BMP-2) Aggregates Can be Solubilized by Albumin—Investigation of BMP-2 Aggregation by Light Scattering and Electrophoresis

Bone morphogenetic protein 2 (BMP-2) has a high tendency to aggregate at physiological pH and physiological ionic strength, which can complicate the development of growth factor delivery systems. The aggregation behavior in differently concentrated BMP-2 solutions was investigated using dynamic and...

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Detalles Bibliográficos
Autores principales: Sundermann, Julius, Zagst, Holger, Kuntsche, Judith, Wätzig, Hermann, Bunjes, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760923/
https://www.ncbi.nlm.nih.gov/pubmed/33255722
http://dx.doi.org/10.3390/pharmaceutics12121143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760923/
https://www.ncbi.nlm.nih.gov/pubmed/33255722
http://dx.doi.org/10.3390/pharmaceutics12121143

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