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Bone Morphogenetic Protein 2 (BMP-2) Aggregates Can be Solubilized by Albumin—Investigation of BMP-2 Aggregation by Light Scattering and Electrophoresis
Bone morphogenetic protein 2 (BMP-2) has a high tendency to aggregate at physiological pH and physiological ionic strength, which can complicate the development of growth factor delivery systems. The aggregation behavior in differently concentrated BMP-2 solutions was investigated using dynamic and...
Autores principales: | Sundermann, Julius, Zagst, Holger, Kuntsche, Judith, Wätzig, Hermann, Bunjes, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760923/ https://www.ncbi.nlm.nih.gov/pubmed/33255722 http://dx.doi.org/10.3390/pharmaceutics12121143 |
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