DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells

SIMPLE SUMMARY: Dyskerin is a nucleolar protein involved in the modification and processing of ribosomal RNA and in the stabilization of the telomerase RNA component. In several human tumors, including breast cancer, dyskerin overexpression is found related to patients’ worse prognosis. Our aim was...

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Detalles Bibliográficos
Autores principales: Guerrieri, Ania Naila, Zacchini, Federico, Onofrillo, Carmine, Di Viggiano, Sara, Penzo, Marianna, Ansuini, Alessio, Gandin, Ilaria, Nobe, Yuko, Taoka, Masato, Isobe, Toshiaki, Treré, Davide, Montanaro, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760958/
https://www.ncbi.nlm.nih.gov/pubmed/33255756
http://dx.doi.org/10.3390/cancers12123512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760958/
https://www.ncbi.nlm.nih.gov/pubmed/33255756
http://dx.doi.org/10.3390/cancers12123512

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