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Implications of ABCC4–Mediated cAMP Efflux for CRC Migration

SIMPLE SUMMARY: Cancer cells have developed a number of mechanisms to overcome anticancer therapy; the active efflux of drugs from cells via multidrug resistance proteins (MRPs) is one of them. MRPs belong to the superfamily of ATP binding cassette (ABC) proteins. It was hypothesized that the inhibi...

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Detalles Bibliográficos
Autores principales: Kryczka, Jakub, Sochacka, Ewelina, Papiewska-Pająk, Izabela, Boncela, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760996/
https://www.ncbi.nlm.nih.gov/pubmed/33261018
http://dx.doi.org/10.3390/cancers12123547