Interleukin-34 Enhances the Tumor Promoting Function of Colorectal Cancer-Associated Fibroblasts

SIMPLE SUMMARY: In colorectal cancer (CRC), cancer-associated fibroblasts (CAFs) promote tumor growth and progression through the synthesis of various molecules targeting the neoplastic cells. Here, we demonstrate that IL-34, a cytokine highly expressed in CRC tissue, regulates the function of CAFs...

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Detalles Bibliográficos
Autores principales: Franzè, Eleonora, Di Grazia, Antonio, Sica, Giuseppe Sigismondo, Biancone, Livia, Laudisi, Federica, Monteleone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761053/
https://www.ncbi.nlm.nih.gov/pubmed/33260828
http://dx.doi.org/10.3390/cancers12123537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761053/
https://www.ncbi.nlm.nih.gov/pubmed/33260828
http://dx.doi.org/10.3390/cancers12123537

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