An Anti-MICA/B Antibody and IL-15 Rescue Altered NKG2D-Dependent NK Cell Responses in Hepatocellular Carcinoma

SIMPLE SUMMARY: Primary liver cancer is one of the most common causes of cancer-related deaths worldwide. The present study shows that the cytokine IL-15 and a humanized antibody specific for a ligand recognized by a major activating receptor (NKG2D) expressed by a subset of lymphocytes named natura...

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Detalles Bibliográficos
Autores principales: Mantovani, Stefania, Varchetta, Stefania, Mele, Dalila, Donadon, Matteo, Torzilli, Guido, Soldani, Cristiana, Franceschini, Barbara, Porta, Camillo, Chiellino, Silvia, Pedrazzoli, Paolo, Santambrogio, Roberto, Barabino, Matteo, Cigala, Claudia, Piccolo, Gaetano, Opocher, Enrico, Maestri, Marcello, Sangiovanni, Angelo, Bernuzzi, Stefano, Lhospice, Florence, Kraiem, Manel, Mondelli, Mario Umberto, Oliviero, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761065/
https://www.ncbi.nlm.nih.gov/pubmed/33266137
http://dx.doi.org/10.3390/cancers12123583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761065/
https://www.ncbi.nlm.nih.gov/pubmed/33266137
http://dx.doi.org/10.3390/cancers12123583

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