Differential Effects of Cancer-Associated Mutations Enriched in Helix H3 of PPARγ

SIMPLE SUMMARY: The high frequency of mutations in helix H3 of the peroxisome proliferator-activated receptor gamma (PPARγ) ligand-binding domain (LBD) in various cancers suggest that this region has an important role in tumorigenesis. In this study, we performed bioinformatics, structural and bioch...

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Detalles Bibliográficos
Autores principales: Jang, Dong Man, Jang, Jun Young, Kim, Hyun-Jung, Han, Byung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761077/
https://www.ncbi.nlm.nih.gov/pubmed/33266062
http://dx.doi.org/10.3390/cancers12123580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761077/
https://www.ncbi.nlm.nih.gov/pubmed/33266062
http://dx.doi.org/10.3390/cancers12123580

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