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Differential Effects of Cancer-Associated Mutations Enriched in Helix H3 of PPARγ
SIMPLE SUMMARY: The high frequency of mutations in helix H3 of the peroxisome proliferator-activated receptor gamma (PPARγ) ligand-binding domain (LBD) in various cancers suggest that this region has an important role in tumorigenesis. In this study, we performed bioinformatics, structural and bioch...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761077/ https://www.ncbi.nlm.nih.gov/pubmed/33266062 http://dx.doi.org/10.3390/cancers12123580 |