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New Pieces in the Puzzle of uPAR Role in Cell Migration Mechanisms

The urokinase (uPA) receptor (uPAR) plays a key role in cell migration. We previously showed that uPAR-negative HEK-293 cells efficiently migrate toward serum but, after uPAR ectopic expression, migrate only in a uPAR-dependent manner. In fact, migration of uPAR-transfected HEK-293 (uPAR-293) cells...

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Detalles Bibliográficos
Autores principales: Gorrasi, Anna, Petrone, Anna Maria, Li Santi, Anna, Alfieri, Mariaevelina, Montuori, Nunzia, Ragno, Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761155/
https://www.ncbi.nlm.nih.gov/pubmed/33255171
http://dx.doi.org/10.3390/cells9122531