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Good Cop, Bad Cop: The Opposing Effects of Macrophage Activation State on Maintaining or Damaging Functional β-Cell Mass

Loss of functional β-cell mass is a hallmark of Type 1 and Type 2 Diabetes. Macrophages play an integral role in the maintenance or destruction of pancreatic β-cells. The effect of the macrophage β-cell interaction is dependent on the activation state of the macrophage. Macrophages can be activated...

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Detalles Bibliográficos
Autores principales: Jensen, Daelin M., Hendricks, Kyle V., Mason, Austin T., Tessem, Jeffery S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761161/
https://www.ncbi.nlm.nih.gov/pubmed/33256225
http://dx.doi.org/10.3390/metabo10120485