Proposal of Potent Inhibitors for a Bacterial Cell Division Protein FtsZ: Molecular Simulations Based on Molecular Docking and ab Initio Molecular Orbital Calculations

The inhibition of a bacterial cell division protein, filamentous temperature-sensitive Z (FtsZ), prevents the reproduction of Mycobacteria. To propose potent inhibitors of FtsZ, the binding properties of FtsZ with various derivatives of Zantrin ZZ3 were investigated at an electronic level, using mol...

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Detalles Bibliográficos
Autores principales: Yamamoto, Shohei, Saito, Ryosuke, Nakamura, Shunya, Sogawa, Haruki, Karpov, Pavel, Shulga, Sergey, Blume, Yaroslav, Kurita, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761175/
https://www.ncbi.nlm.nih.gov/pubmed/33256135
http://dx.doi.org/10.3390/antibiotics9120846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761175/
https://www.ncbi.nlm.nih.gov/pubmed/33256135
http://dx.doi.org/10.3390/antibiotics9120846

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