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Single-Cell Spatial Analysis of Tumor and Immune Microenvironment on Whole-Slide Image Reveals Hepatocellular Carcinoma Subtypes

SIMPLE SUMMARY: Current molecular classification systems are primarily based on cancer-cell-intrinsic features, which disregard the critical contribution of the microenvironment and lack spatial information. Here, we take a holistic approach by incorporating spatial imaging phenotypes of both tumor...

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Detalles Bibliográficos
Autores principales: Wang, Haiyue, Jiang, Yuming, Li, Bailiang, Cui, Yi, Li, Dengwang, Li, Ruijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761227/
https://www.ncbi.nlm.nih.gov/pubmed/33260561
http://dx.doi.org/10.3390/cancers12123562