Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates

Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder with heterotopic ossification (HO) in soft tissues. The abnormal activation of bone morphogenetic protein (BMP) signaling by a mutant activin receptor-like kinase-2 (ALK2) leads to the development of HO in FOP patients, and, t...

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Detalles Bibliográficos
Autores principales: Yamazaki, Hiroyuki, Ohte, Satoshi, Rotinsulu, Henki, Wewengkang, Defny S., Sumilat, Deiske A., Abdjul, Delfly B., Maarisit, Wilmar, Kapojos, Magie M., Namikoshi, Michio, Katagiri, Takenobu, Tomoda, Hiroshi, Uchida, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761252/
https://www.ncbi.nlm.nih.gov/pubmed/33265937
http://dx.doi.org/10.3390/md18120606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761252/
https://www.ncbi.nlm.nih.gov/pubmed/33265937
http://dx.doi.org/10.3390/md18120606

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