Cargando…
Screening for Small Molecule Inhibitors of BMP-Induced Osteoblastic Differentiation from Indonesian Marine Invertebrates
Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder with heterotopic ossification (HO) in soft tissues. The abnormal activation of bone morphogenetic protein (BMP) signaling by a mutant activin receptor-like kinase-2 (ALK2) leads to the development of HO in FOP patients, and, t...
Autores principales: | Yamazaki, Hiroyuki, Ohte, Satoshi, Rotinsulu, Henki, Wewengkang, Defny S., Sumilat, Deiske A., Abdjul, Delfly B., Maarisit, Wilmar, Kapojos, Magie M., Namikoshi, Michio, Katagiri, Takenobu, Tomoda, Hiroshi, Uchida, Ryuji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761252/ https://www.ncbi.nlm.nih.gov/pubmed/33265937 http://dx.doi.org/10.3390/md18120606 |
Ejemplares similares
-
A polybromodiphenyl ether from an Indonesian marine sponge Lamellodysideaherbacea and its chemical derivatives inhibit protein tyrosine phosphatase 1B, an important target for diabetes treatment
por: Yamazaki, Hiroyuki, et al.
Publicado: (2012) -
Two New Tryptamine Derivatives, Leptoclinidamide and (-)-Leptoclinidamine B, from an Indonesian Ascidian Leptoclinides dubius
por: Yamazaki, Hiroyuki, et al.
Publicado: (2012) -
A New Dibenz[b, e]oxepine Derivative, 1-Hydroxy-10-methoxy-dibenz[b, e]oxepin-6,11-dione, from a Marine-Derived Fungus, Beauveria bassiana TPU942
por: Yamazaki, Hiroyuki, et al.
Publicado: (2012) -
Isolation of C(11) Compounds and a Cyclopropane Fatty Acid from an Okinawan Ascidian, Diplosoma sp.
por: Rob, Tamanna, et al.
Publicado: (2011) -
Chemical Diversity and Biological Activity of Secondary Metabolites Isolated from Indonesian Marine Invertebrates
por: Izzati, Fauzia, et al.
Publicado: (2021)