Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells

Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of alternative splicing. To understand which GBA2 isofo...

Descripción completa

Detalles Bibliográficos
Autores principales: Jatooratthawichot, Peeranat, Talabnin, Chutima, Ngiwsara, Lukana, Rustam, Yepy Hardi, Svasti, Jisnuson, Reid, Gavin E., Ketudat Cairns, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761373/
https://www.ncbi.nlm.nih.gov/pubmed/33261081
http://dx.doi.org/10.3390/metabo10120488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761373/
https://www.ncbi.nlm.nih.gov/pubmed/33261081
http://dx.doi.org/10.3390/metabo10120488

Ejemplares similares