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Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of alternative splicing. To understand which GBA2 isofo...
Autores principales: | Jatooratthawichot, Peeranat, Talabnin, Chutima, Ngiwsara, Lukana, Rustam, Yepy Hardi, Svasti, Jisnuson, Reid, Gavin E., Ketudat Cairns, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761373/ https://www.ncbi.nlm.nih.gov/pubmed/33261081 http://dx.doi.org/10.3390/metabo10120488 |
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