Pseudomonas Exotoxin A Based Toxins Targeting Epidermal Growth Factor Receptor for the Treatment of Prostate Cancer

The epidermal growth factor receptor (EGFR) was found to be a valuable target on prostate cancer (PCa) cells. However, EGFR inhibitors mostly failed in clinical studies with patients suffering from PCa. We therefore tested the targeted toxins EGF-PE40 and EGF-PE24mut consisting of the natural ligand...

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Detalles Bibliográficos
Autores principales: Fischer, Alexandra, Wolf, Isis, Fuchs, Hendrik, Masilamani, Anie Priscilla, Wolf, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761469/
https://www.ncbi.nlm.nih.gov/pubmed/33260619
http://dx.doi.org/10.3390/toxins12120753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761469/
https://www.ncbi.nlm.nih.gov/pubmed/33260619
http://dx.doi.org/10.3390/toxins12120753

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