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Pathogenic Germline Mutations of DNA Repair Pathway Components in Early-Onset Sporadic Colorectal Polyp and Cancer Patients

SIMPLE SUMMARY: Colorectal cancer (CRC) screening by immuno-fecal occult blood tests (iFOBTs) begins at age 50 in average-risk persons. However, the incidence of early-onset CRC has risen; of the cases, at least half are sporadic CRC without a family history. The authors of this study found a high p...

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Detalles Bibliográficos
Autores principales: Chang, Pi-Yueh, Chang, Shih-Cheng, Wang, Mei-Chia, Chen, Jinn-Shiun, Tsai, Wen-Sy, You, Jeng-Fu, Chen, Chia-Chun, Liu, Hsiu-Ling, Chiang, Jy-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761471/
https://www.ncbi.nlm.nih.gov/pubmed/33260537
http://dx.doi.org/10.3390/cancers12123560