Acylpolyamine Mygalin as a TLR4 Antagonist Based on Molecular Docking and In Vitro Analyses

Toll-like receptors (TLRs) are transmembrane proteins that are key regulators of innate and adaptive immune responses, particularly TLR4, and they have been identified as potential drug targets for the treatment of disease. Several low-molecular-weight compounds are being considered as new drug targ...

Descripción completa

Detalles Bibliográficos
Autores principales: Espinoza-Culupú, Abraham, Vázquez-Ramírez, Ricardo, Farfán-López, Mariella, Mendes, Elizabeth, Notomi Sato, Maria, da Silva Junior, Pedro Ismael, Borges, Monamaris Marques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761503/
https://www.ncbi.nlm.nih.gov/pubmed/33271940
http://dx.doi.org/10.3390/biom10121624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761503/
https://www.ncbi.nlm.nih.gov/pubmed/33271940
http://dx.doi.org/10.3390/biom10121624

Ejemplares similares