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Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability

Dengue virus (DENV), an arbovirus, strongly activates mast cells (MCs), which are key immune cells for pathogen immune surveillance. In animal models, MCs promote clearance of local peripheral DENV infections but, conversely, also promote pathological vascular leakage when widely activated during sy...

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Detalles Bibliográficos
Autores principales: Syenina, Ayesa, Saron, Wilfried A. A., Jagaraj, Cyril J., Bibi, Siham, Arock, Michel, Gubler, Duane J., Rathore, Abhay P. S., Abraham, Soman N., St. John, Ashley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761533/
https://www.ncbi.nlm.nih.gov/pubmed/33276578
http://dx.doi.org/10.3390/v12121379