3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease

The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel disease. Blends of Gelucire 44/14 and coconut oil were employed as lipid excip...

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Detalles Bibliográficos
Autores principales: Seoane-Viaño, Iria, Gómez-Lado, Noemí, Lázare-Iglesias, Héctor, García-Otero, Xurxo, Antúnez-López, José Ramón, Ruibal, Álvaro, Varela-Correa, Juan Jesús, Aguiar, Pablo, Basit, Abdul W., Otero-Espinar, Francisco J., González-Barcia, Miguel, Goyanes, Alvaro, Luzardo-Álvarez, Asteria, Fernández-Ferreiro, Anxo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761558/
https://www.ncbi.nlm.nih.gov/pubmed/33276641
http://dx.doi.org/10.3390/biomedicines8120563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761558/
https://www.ncbi.nlm.nih.gov/pubmed/33276641
http://dx.doi.org/10.3390/biomedicines8120563

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