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3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease
The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel disease. Blends of Gelucire 44/14 and coconut oil were employed as lipid excip...
Autores principales: | Seoane-Viaño, Iria, Gómez-Lado, Noemí, Lázare-Iglesias, Héctor, García-Otero, Xurxo, Antúnez-López, José Ramón, Ruibal, Álvaro, Varela-Correa, Juan Jesús, Aguiar, Pablo, Basit, Abdul W., Otero-Espinar, Francisco J., González-Barcia, Miguel, Goyanes, Alvaro, Luzardo-Álvarez, Asteria, Fernández-Ferreiro, Anxo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761558/ https://www.ncbi.nlm.nih.gov/pubmed/33276641 http://dx.doi.org/10.3390/biomedicines8120563 |
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