NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis

SIMPLE SUMMARY: Transcription factor NRF2 controls expression of antioxidant and detoxification genes. Normally, the activity of NRF2 is tightly controlled in the cell, and is continuously adjusted to ensure that cells are protected against endogenous chemicals and environmental agents that perturb...

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Detalles Bibliográficos
Autores principales: Robertson, Holly, Dinkova-Kostova, Albena T., Hayes, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761610/
https://www.ncbi.nlm.nih.gov/pubmed/33276631
http://dx.doi.org/10.3390/cancers12123609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761610/
https://www.ncbi.nlm.nih.gov/pubmed/33276631
http://dx.doi.org/10.3390/cancers12123609

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