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Commensal Bacterium Rothia aeria Degrades and Detoxifies Gluten via a Highly Effective Subtilisin Enzyme

Celiac disease is characterized by a chronic immune-mediated inflammation of the small intestine, triggered by gluten contained in wheat, barley, and rye. Rothia aeria, a gram-positive natural colonizer of the oral cavity and the upper digestive tract is able to degrade and detoxify gluten in vitro....

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Detalles Bibliográficos
Autores principales: Wei, Guoxian, Darwish, Ghassan, Oppenheim, Frank G., Schuppan, Detlef, Helmerhorst, Eva J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761627/
https://www.ncbi.nlm.nih.gov/pubmed/33276655
http://dx.doi.org/10.3390/nu12123724