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Role of HMGB1/TLR4 Axis in Ischemia/Reperfusion-Impaired Extracellular Glutamate Clearance in Primary Astrocytes

(1) Background: Abnormal accumulation of extracellular glutamate can occur as dysfunction of astrocytic glutamate transporters, which has been linked to ischemic brain injury. Excessive extracellular glutamate-induced abnormal excitotoxicity is the major cause of secondary neuronal damage after cere...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Ho, Chen, Han-Yu, Wei, Kai-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761728/
https://www.ncbi.nlm.nih.gov/pubmed/33287126
http://dx.doi.org/10.3390/cells9122585