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Apigenin Increases SHIP-1 Expression, Promotes Tumoricidal Macrophages and Anti-Tumor Immune Responses in Murine Pancreatic Cancer

SIMPLE SUMMARY: Src Homology 2 (SH2) domain-containing Inositol 5’-Phosphatase-1 (SHIP-1) is an essential protein and the master regulator of myeloid cell development and function that impacts tumor immunity. We previously published that SHIP-1 regulates the expansion and function of immunosuppressi...

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Detalles Bibliográficos
Autores principales: Villalobos-Ayala, Krystal, Ortiz Rivera, Ivannie, Alvarez, Ciara, Husain, Kazim, DeLoach, DeVon, Krystal, Gerald, Hibbs, Margaret L., Jiang, Kun, Ghansah, Tomar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761852/
https://www.ncbi.nlm.nih.gov/pubmed/33291556
http://dx.doi.org/10.3390/cancers12123631