Growth Hormone Upregulates Mediators of Melanoma Drug Efflux and Epithelial-to-Mesenchymal Transition In Vitro and In Vivo

SIMPLE SUMMARY: Growth hormone (GH) action is strongly implicated in the progression and therapy resistance in several types of solid tumors which overexpress the GH receptor (GHR). The aim of our study was to characterize the effects of GH and its downstream effector insulin-like growth factor 1 (I...

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Detalles Bibliográficos
Autores principales: Qian, Yanrong, Basu, Reetobrata, Mathes, Samuel C., Arnett, Nathan A., Duran-Ortiz, Silvana, Funk, Kevin R., Brittain, Alison L., Kulkarni, Prateek, Terry, Joseph C., Davis, Emily, Singerman, Jordyn T., Henry, Brooke E., List, Edward O., Berryman, Darlene E., Kopchick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761932/
https://www.ncbi.nlm.nih.gov/pubmed/33291663
http://dx.doi.org/10.3390/cancers12123640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761932/
https://www.ncbi.nlm.nih.gov/pubmed/33291663
http://dx.doi.org/10.3390/cancers12123640

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