Global Autozygosity Is Associated with Cancer Risk, Mutational Signature and Prognosis

SIMPLE SUMMARY: Global autozygosity in the form of runs of homozygosity is associated with various diseases. Heterozygosity ratio, an alternative measure of global autozygosity, is used to assess cancer risk in this study. Our analysis shows strong and consistent associations between heterozygosity...

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Detalles Bibliográficos
Autores principales: Jiang, Limin, Guo, Fei, Tang, Jijun, Leng, Shuguan, Ness, Scott, Ye, Fei, Kang, Huining, Samuels, David C., Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761949/
https://www.ncbi.nlm.nih.gov/pubmed/33291726
http://dx.doi.org/10.3390/cancers12123646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761949/
https://www.ncbi.nlm.nih.gov/pubmed/33291726
http://dx.doi.org/10.3390/cancers12123646

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