Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

Hypoxia is a condition commonly observed in the core of solid tumors. The hypoxia-inducible factors (HIF) act as hypoxia sensors that orchestrate a coordinated response increasing the pro-survival and pro-invasive phenotype of cancer cells, and determine a broad metabolic rewiring. These events favo...

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Detalles Bibliográficos
Autores principales: Belisario, Dimas Carolina, Kopecka, Joanna, Pasino, Martina, Akman, Muhlis, De Smaele, Enrico, Donadelli, Massimo, Riganti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761956/
https://www.ncbi.nlm.nih.gov/pubmed/33291643
http://dx.doi.org/10.3390/cells9122598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761956/
https://www.ncbi.nlm.nih.gov/pubmed/33291643
http://dx.doi.org/10.3390/cells9122598

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