NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data

Ionotropic GABA transmission is mediated by anion (mainly Cl(−))-permeable GABA(A) receptors (GABA(A)Rs). In immature neurons, GABA exerts depolarizing and sometimes functionally excitatory actions, based on active uptake of Cl(−) by the Na-K-2Cl cotransporter NKCC1. While functional evidence firmly...

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Detalles Bibliográficos
Autores principales: Virtanen, Mari A., Uvarov, Pavel, Hübner, Christian A., Kaila, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761970/
https://www.ncbi.nlm.nih.gov/pubmed/33291778
http://dx.doi.org/10.3390/cells9122607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761970/
https://www.ncbi.nlm.nih.gov/pubmed/33291778
http://dx.doi.org/10.3390/cells9122607

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