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NKCC1, an Elusive Molecular Target in Brain Development: Making Sense of the Existing Data
Ionotropic GABA transmission is mediated by anion (mainly Cl(−))-permeable GABA(A) receptors (GABA(A)Rs). In immature neurons, GABA exerts depolarizing and sometimes functionally excitatory actions, based on active uptake of Cl(−) by the Na-K-2Cl cotransporter NKCC1. While functional evidence firmly...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761970/ https://www.ncbi.nlm.nih.gov/pubmed/33291778 http://dx.doi.org/10.3390/cells9122607 |