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Tolerant/Persister Cancer Cells and the Path to Resistance to Targeted Therapy
The capacity of cancer to adapt to treatment and evolve is a major limitation for targeted therapies. While the role of new acquired mutations is well-established, recent findings indicate that resistance can also arise from subpopulations of tolerant/persister cells that survive in the presence of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761971/ https://www.ncbi.nlm.nih.gov/pubmed/33291749 http://dx.doi.org/10.3390/cells9122601 |