Molecular Docking Simulations on Histone Deacetylases (HDAC)-1 and -2 to Investigate the Flavone Binding

Histone modifications through acetylation are fundamental for remodelling chromatin and consequently activating gene expression. The imbalance between acetylation and deacetylation activity causes transcriptional dysregulation associated with several disorders. Flavones, small molecules of plant ori...

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Detalles Bibliográficos
Autores principales: Scafuri, Bernardina, Bontempo, Paola, Altucci, Lucia, De Masi, Luigi, Facchiano, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761979/
https://www.ncbi.nlm.nih.gov/pubmed/33291755
http://dx.doi.org/10.3390/biomedicines8120568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761979/
https://www.ncbi.nlm.nih.gov/pubmed/33291755
http://dx.doi.org/10.3390/biomedicines8120568

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