Targeting MDM2 for Neuroblastoma Therapy: In Vitro and In Vivo Anticancer Activity and Mechanism of Action

SIMPLE SUMMARY: Neuroblastoma is a malignant tumor of the sympathetic nervous system that causes aggressive disease in children. The overall survival rate of high-risk patients is very low, therefore developing effective and safe therapies for neuroblastoma is an urgent unmet medical need. The mouse...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Xinjie, Rajaei, Mehrdad, Youn, Ji Youn, Zafar, Atif, Deokar, Hemantkumar, Buolamwini, John K., Yang, Jianhua, Foster, Jennifer H., Zhou, Jia, Zhang, Ruiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762001/
https://www.ncbi.nlm.nih.gov/pubmed/33291373
http://dx.doi.org/10.3390/cancers12123651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762001/
https://www.ncbi.nlm.nih.gov/pubmed/33291373
http://dx.doi.org/10.3390/cancers12123651

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