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MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation

SIMPLE SUMMARY: Glioblastoma (GBM) is the most lethal brain tumor with a median survival rate of approximately 14 months. GBM patients commonly suffer from tumor recurrence, indicating that populations of chemo/radio-resistant stem cell-like tumor cells survive treatments. Here we reveal that the ne...

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Detalles Bibliográficos
Autores principales: Pötschke, Rebecca, Haase, Jacob, Glaß, Markus, Simmermacher, Sebastian, Misiak, Claudia, Penalva, Luiz O. F., Kühnöl, Caspar D., Hüttelmaier, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762192/
https://www.ncbi.nlm.nih.gov/pubmed/33291443
http://dx.doi.org/10.3390/cancers12123654