Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

SIMPLE SUMMARY: Thrombocytosis correlates with poor prognosis for treatment of malignant melanoma. Detailed information on how platelets modify the anti-tumoral immune response is still elusive. Analyzing the immunomodulatory capacities of platelets on huCD4(+) T cells in vitro, we were able to show...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimmer, Niklas, Krebs, Franziska K., Zimmer, Sophia, Mitzel-Rink, Heidrun, Kumm, Elena J., Jurk, Kerstin, Grabbe, Stephan, Loquai, Carmen, Tuettenberg, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762193/
https://www.ncbi.nlm.nih.gov/pubmed/33291452
http://dx.doi.org/10.3390/cancers12123653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762193/
https://www.ncbi.nlm.nih.gov/pubmed/33291452
http://dx.doi.org/10.3390/cancers12123653

Ejemplares similares