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Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

SIMPLE SUMMARY: Thrombocytosis correlates with poor prognosis for treatment of malignant melanoma. Detailed information on how platelets modify the anti-tumoral immune response is still elusive. Analyzing the immunomodulatory capacities of platelets on huCD4(+) T cells in vitro, we were able to show...

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Detalles Bibliográficos
Autores principales:	Zimmer, Niklas, Krebs, Franziska K., Zimmer, Sophia, Mitzel-Rink, Heidrun, Kumm, Elena J., Jurk, Kerstin, Grabbe, Stephan, Loquai, Carmen, Tuettenberg, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762193/ https://www.ncbi.nlm.nih.gov/pubmed/33291452 http://dx.doi.org/10.3390/cancers12123653

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