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Analgesic Tolerance Development during Repetitive Electric Stimulations Is Associated with Changes in the Expression of Activated Microglia in Rats with Osteoarthritis

Electric stimulation is used for managing osteoarthritic (OA) pain; however, little is known about the development of analgesic tolerance during repeated stimulations and the relation of spinal microglia with OA pain. We investigated the changes in the analgesic effects of repeated electric stimulat...

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Detalles Bibliográficos
Autores principales: Hahm, Suk-Chan, Lee, Jin Seung, Yoon, Young Wook, Kim, Junesun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762208/
https://www.ncbi.nlm.nih.gov/pubmed/33297333
http://dx.doi.org/10.3390/biomedicines8120575