Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority of promising preclinical drugs have no or weak efficacy in real patients with tumors, thereby delaying the discov...

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Detalles Bibliográficos
Autores principales: Pinto, Bárbara, Henriques, Ana C., Silva, Patrícia M. A., Bousbaa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762220/
https://www.ncbi.nlm.nih.gov/pubmed/33291351
http://dx.doi.org/10.3390/pharmaceutics12121186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762220/
https://www.ncbi.nlm.nih.gov/pubmed/33291351
http://dx.doi.org/10.3390/pharmaceutics12121186

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