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Intravenous Administration of Coenzyme Q10 in Acute Period of Cerebral Ischemia Decreases Mortality by Reducing Brain Necrosis and Limiting Its Increase within 4 Days in Rat Stroke Model

Oxidative stress plays a key role in the pathogenesis of ischemic stroke. Coenzyme Q10 has a multi-targeting effect and may protect the brain against ischemic damage. The aim of our study was to evaluate the neuroprotective potential of ubiquinol by its intravenous administration. The study was perf...

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Detalles Bibliográficos
Autores principales: Olga Nikolaevna, Obolenskaia, Evgeniya Aronovna, Gorodetskaya, Elena Igorevna, Kalenikova, Margarita Alekseevna, Belousova, Mikhail Vladimirovich, Gulyaev, Valery Gennadievich, Makarov, Yury Andreevich, Pirogov, Oleg Stephanovich, Medvedev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762283/
https://www.ncbi.nlm.nih.gov/pubmed/33297323
http://dx.doi.org/10.3390/antiox9121240