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Plant TDP1 (Tyrosyl-DNA Phosphodiesterase 1): A Phylogenetic Perspective and Gene Expression Data Mining

The TDP1 (tyrosyl-DNA phosphodiesterase 1) enzyme removes the non-specific covalent intermediates between topoisomerase I and DNA, thus playing a crucial role in preventing DNA damage. While mammals possess only one TDP1 gene, in plants two genes (TDP1α and TDP1β) are present constituting a small ge...

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Detalles Bibliográficos
Autores principales: Mutti, Giacomo, Raveane, Alessandro, Pagano, Andrea, Bertolini, Francesco, Semino, Ornella, Balestrazzi, Alma, Macovei, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762302/
https://www.ncbi.nlm.nih.gov/pubmed/33297410
http://dx.doi.org/10.3390/genes11121465