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Mutations and Copy Number Alterations in IDH Wild-Type Glioblastomas Are Shaped by Different Oncogenic Mechanisms

Little is known about the mutational processes that shape the genetic landscape of gliomas. Numerous mutational processes leave marks on the genome in the form of mutations, copy number alterations, rearrangements or their combinations. To explore gliomagenesis, we hypothesized that gliomas with dif...

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Detalles Bibliográficos
Autores principales: Ülgen, Ege, Karacan, Sıla, Gerlevik, Umut, Can, Özge, Bilguvar, Kaya, Oktay, Yavuz, B. Akyerli, Cemaliye, K. Yüksel, Şirin, E. Danyeli, Ayça, Tihan, Tarık, Sezerman, O. Uğur, Yakıcıer, M. Cengiz, Pamir, M. Necmettin, Özduman, Koray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762325/
https://www.ncbi.nlm.nih.gov/pubmed/33297360
http://dx.doi.org/10.3390/biomedicines8120574