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Drug-Eluting Biodegradable Implants for the Sustained Release of Bisphosphonates

Despite being one of the first-line treatments for osteoporosis, the bisphosphonate drug class exhibits an extremely low oral bioavailability (<1%) due to poor absorption from the gastrointestinal tract. To overcome this, and to explore the potential for sustained drug release, bioerodible poly(l...

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Detalles Bibliográficos
Autores principales: Dharmayanti, Cintya, Gillam, Todd A., Williams, Desmond B., Blencowe, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762379/
https://www.ncbi.nlm.nih.gov/pubmed/33297466
http://dx.doi.org/10.3390/polym12122930